Hello all, apologies in advance for what will undoubtedly be a long read! I have a 10 year old tomcat who recently started exhibiting some very strange behaviour. I thought it might be his eyesight because he had an eye infection about 2 months ago which made him a little clumsy (but it cleared up within a week following treatment and he was back to normal), but this was a bit more extreme; wandering around the house pretty aimlessly, walking towards the hinged side of doors, unwilling to jump onto/off things etc. And the days leading up to when we went to the vets he was off his food, which was completely out of character. So I took him to the vets and following an overnight stay and numerous tests I got the horrible news that he has both Feline Leukaemia and AIDS. The vet did say that cats can live for years with these conditions, but if they get into a bad spell, sometimes they'll simply go downhill and never come out of it. Not what I wanted to hear. The vet gave me some anti-inflammatories to make him feel a bit better and get him to eat some food, and when we got him home he was back to his old self. Very active, purring like an engine, eating everything we put in front of him, all positive signs! But the last few days have been a nightmare. He seems to be extremely disorientated because he's just plodding around the house, going to areas he never usually goes and pressing his head against the wall. He won't jump anywhere, even onto the sofa which was his favourite sleeping spot (I lifted him onto it and it took him around 5 minutes of groping with his paw over the edge before he actually got down, and even then he landed awkwardly), and he seems to be permanently uncomfortable as he's not purring, his claws are out and he's adopting positions he wouldn't normally. And he's off his food again. I left him a veritable kitty banquet - a bowl of Sheba, a bowl of crunchy food, a bowl of cut-up chicken fillet, and a bowl of water. Apart from sniffing the Sheba and licking it briefly, he hasn't touched any of it. He has always been a *big* meat eater, chicken especially. If he knew there was a scrap of chicken in the fridge he'd sit camped outside it until it was opened and he'd devour it, so for him to ignore it completely is very worrying. He always went out to go to the toilet as opposed to using a litter tray, and he'd always let us know when he wanted to go out by sitting at the door and ringing his "doorbell" (a newspaper he'd flick repeatedly), and regardless how long he was left in the house never went indoors. But I came downstairs the other morning to find a pool of urine on the kitchen floor, strangely odourless. I put him outside to see if it might jog his memory but he just sat there huddled up until I let him back in. And now any time I let him out, he goes to a spot next to the door and starts licking the ground! I admit I have pretty much no knowledge of FIV/FeLV, but from reading other peoples' experiences, for the most part when it occurred in their cats it was somewhat of a gradual decline over a period of months. But with my cat it was *literally* overnight. And he's always been as healthy as a horse. Neutered and vaccinated when he was young, and in 10 years only needed to visit the vet's twice - an infected paw in 2009 and the more recent eye infection. He used to sometimes vomit up his food but that was due to him eating too much too fast. He was always a tad overweight, not obese but very solid. He had lost a little bit of weight over the last year or so, but nothing noticeable and nothing out of the ordinary for a cat of his age. But in the last several days he's gone from healthy to skin and bones, and it's shocking to look at him. I was wondering if anyone else in the forum has gone through the same thing with their own moggies? Or from the symptoms above, does it sound like it could be something else? I don't want to second guess the vet but a decline of this magnitude in such a short space of time just seems bizarre. He's had all his blood work done and his kidney function is fine, had an x-ray and there's no bone damage, had a biopsy but nothing cancerous. So apart from perhaps getting a second opinion I can't think of anything else. Any responses would be appreciated!