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PetForums VIP, from Cumbria
How are you.
Ello my lovely; how's the spying going? Love ya xxxx
Omg you're alive :p
Ello my gorgeous lady xxxx
Jules? Can you empty some of your inbox so I can PM you please xxxx
Cousin had to have her bull terrier Buster put to sleep. He was old and wasn't well, I said to mum it's about Busters quality of life at the end of the day.
That's great news. Glad you have seen a difference already, you must feel better too now you know it was deffinately the right thing for him.
Part 2. Ignore the mention of seizures its about them too, but both are behavioural.
Behavioral changes associated with thyroid dysfunction in dogs.
Are your dogs seizures caused by Canine Epilepsy or Autoimmune Thyroiditis?
They are both by Jean Dodds
Your welcome. Just been thinking about his earlier fear and anxiety issues too that I now are a concern of yours as he displayed it in the past. Had a couple of thoughts on that too.
Dogs can enter a second fear period any time between about 6/14 months where stuff that didn't bother them before can start to again so that may be one explanation. Getting back to the thyroid issue too that can also cause behaviour problems too including fear/anxiety and aggressiveness, so that may be another explanation cant remember if Ive give you these links before. You might have seen them but if not worth a read.
The suprelorin does cause them to shrink, so I assume with the withdrawal of it they then return to normal size. With enlarged prostrate, it can cause straining and problems urinating and sometimes doing to the toilet the other way too, as it can squash the urethra and bowel if it gets too enlarged.
Has been known in dogs a year and under. Nanuq was under two when she started to have seizures because of HT and her levels were through the floor. How much does chessie weigh or at the time, because on the checking I noticed in the field trials of suprelorin they hant done any on dogs under 10Kgs.
Enlarged prostrate most common cause is sex hormone linked. The "treatment" for it is castration.
How old was Chessie when he started it, because I noticed too that they say, sexually mature dogs. It also says healthy dogs. If chester is hypo thyroid or was sinking into it prior to the suprelorin, then technically he wouldn't be healthy as such, as thyroid is also an endocrine/hormone problem anyway, just wondering if the effects on him would be different or cause more problems. Like I mentioned too, the thyroid and the adrenals work off the same anterior pituitary axis too. So still wondering, if you mess with one, can it mess other hypothalamic pituitary responses up. Cant find any faming research though.
Ive managed to find these the active ingredient is deslorelin superlorin is just the brand name
Sorry wasn't ignorning you I forgot to log out.
Just found this have a read.
Elevated Sex Hormones in Dogs | petMD
It must be driving you insane but it cant be much fun for him either sounds like its really driving him mad too. I know some males can be worse then others for it but it really seems to be sending him of his trolley and you in the process.
It does say that inititally with suprelorin before it starts to suppress the testosterone it actually causes a surge in hormones, then with continued slow release it suppresses it.
Im still wondering if it has caused an extra surge after being suppressed. Either that or
he would have been like it anyway without it and its just delayed the issue. I suppose at least with castration its totally gone once and for all.
There does seem an extreme lack of data. What I also find the most worrying is the bit I hi lighted in the link too. All the stuffs fine as regards benefits, but is a serious lack of log term effects info and what happens after they come off it.
Ive had a look and while there seems to be a lot on behaviour while the suprelorin is active I can find nothing as regards to follow up studies as to what happens once the stuff has worn off. Unless there have been follow ups and field studies as to after effects I cant see as how they can make claims like that really.
Considering from that link I found they don't seem to know exactly what the Gnhr itself does or the full implications never mind what the suprelorin Gnhr antagonist does longer term, Im seriously beginning to wonder but don't know for sure obviously if using it and suppressing the sex hormones and in turn the testosterone makes it go bananas when they do come off it and then then start producing too much if that makes sense. If steroid drugs can mess with the natural production and function of the adrenal cortex when they have been on them, wondering if the suprelorin can have the same effect in some way.