Hi,
just wondered if anyones dog has had a strange reaction to Advocate flea/worming spot on?

Mia our 7 month Cocker Spaniel has been on it for the last 4 months, last month when she was given the treatment she bacame very erratic trying to rub her body against the wall (this was about 1 hour after application) and she wouldnt settle. Now my boyfriend gave her the monthly application again and she is going nuts (still awake at 03:30am) and is running around like a lunatic!!!

She did not react to it before and now the past two months she turns into a crazy dog running around because it is obviously annoying her. She has not had a skin reaction or any other symtoms apart from the erratic behaviour and wondered if anybody elses dog has had the same reaction?strange behaviour?

Bump!

Anybody heard of any strange side effects with Advocate?

Sorry cant be of much help both my dogs are done with advocate and no side affects at all, they are on it from vet as one has emema and cant have front line. but i do not use it every mth i use it every three mths thats all.

Hi Jeanie,
how old are your dogs? Our vet still advices to Worm mia every month (she is 7 months) I am guessing until she is 1 year.

She was still racing around this morning when I came home from work this morning. She is not her usual self although she still has her appetite she has only just started playing with her toys and playing with me. She hasnt wanted any cuddles today :-(

I know its probably nothing but very weird that she has started acting like this for the last two applications.

Personally I think you should notify the vet and not give another application of Advocate.

Sgurr

Yeah I think I will pop in to see them on my way home tomorrow morning.

Hi Chezza my dogs are 18mths old now so quite a lot older than yours i too think i would have a word with the vet maybe it dosent suit her, let us know how you get on

why not use a different worm and flea treatment if you are worried.

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(formally clare7577)

I gave my cat Advocate (the smaller dose for her size) and she suffered an adverse reaction to this medication, my vet is in the process of completing the relevant form and advising the manufacturer. The morning after applying the solution behind her neck I found Maisey crawling down the garden with her head drooped and unable to walk and unable to hold her head up, it was so frightening to watch, she slumped on the ground and I thought she was going to die. I rushed her to the vets where they kept her in for the rest of the day for observation and carried out neurological examination which turned out to be ok and blood tests which were ok too. I had only taken her to the vets the night before for the Advocate and they were pretty shocked at how ill she was the following morning. She couldnt co-ordinate herself at all, a very horrible side effect and I will never ever ever use this on my cat again.

Just looked up whats actually in Advocate it contains Moxidectin and Imidacloprid
they are the active chemicals. Moxidectin should not be used on certain breeds mainly collie and collie type breeds including Old English Sheepdogs.

Side effects do include those which has been mentioned on the OPs post
4.6 Adverse reactions (frequency and seriousness)
Use of the product may result in transient pruritus in dogs. On rare occasions greasy hair, erythema
and vomiting can occur. These signs disappear without further treatment. The product may, in rare
cases, cause local hypersensitivity reactions. If the animal licks the application site after treatment,
transient neurological signs may be observed infrequently (see section 4.10).
The product tastes bitter. Salivation may occasionally occur if the animal licks the application site
immediately after treatment. This is not a sign of intoxication and disappears within some minutes
without treatment. Correct application will minimise licking of the application sites.
The product may in very rare cases cause at the application site a sensation resulting in transient
behavioural changes such as lethargy, agitation, and inappetence.


For full details see Link:- http://www.myvetmeds.co.uk/assets/do...s/30200010.pdf

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