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Old 28-06-2011, 04:48 PM
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Lightbulb AVAR's Guide to Congenital & Heritable Disorders in Dogs

continuing from condition / disorder #80 -
Quote:
81. Dermatitis, atopic: inflammation and subsequent infection of the skin due to atopy.
(also see #21, 22.)
82. Dermatomyositis: a disease affecting the skin and muscles, usually in the Collie or
Shetland Sheepdog
83. Dermoid cyst: a small growth composed of skin-like structures.
84. Dermoid sinus: similar to a dermoid cyst but usually larger. *Rhodesian Ridgeback
85. Diabetes mellitus: a metabolic disease caused by insulin deficiency and
characterized by the inability to utilize sugars normally.
85a. Digital hyperkeratosis: a condition of Irish Terrier puppies that causes marked
thickening of the foot pads. Affected feet crack, become infected and painful.
86. Discoid lupus erythematosus: a form of autoimmune disease affecting the skin.
87. Dislocation of shoulder: a condition where the bones of the shoulder joint are out
of proper position.
88. Distichiasis: abnormally growing eyelashes.
89. Dwarfism: an abnormality of the normal growth pattern resulting in an undersized
individual.
89a. Dysphagia: inability to swallow properly. (also see #69a.)
90. Dystocia: complications of the birth process (difficult birth).
91. Eclampsia: convulsions usually seen around the time of parturition (whelping).
92. Ectodermal defects: any of a multitude of abnormalities arising from
maldevelopment of the fetal ectoderm (e.g., skin, nervous system, eyes).
93. Ectopic ureters: the ureters (tubes leading from the kidneys to the bladder) do not
empty into the bladder in the normal location.
94. Ectropion: an abnormal rolling out of the eyelids.
94a. Ehlers-Danlos syndrome: a connective tissue disease characterized by loose,
hyperextensible and very fragile skin that tears easily. (also see #72.)
95. Elbow dysplasia: an abnormal development of the elbow joint.
96. Elbow joint malformation: (See #95.)
97. Elbow subluxation: a condition where the elbow joint is loose and out of alignment.
98. Elongated soft palate: the soft palate is abnormally long and causes breathing
disorders.
98a. Encephalitis: an inflammatory condition of the brain causing signs of central
nervous system dysfunction and epilepsy (seizures). A unique form of encephalitis is
prevalent in the Pug and is called “Pug Dog Encephalitis.” (also see #109.)
99. Endocardial fibroelastosis: an abnormal condition of scarring of the muscles of
the heart.
100. Endometritis: inflammation of the internal layer of the uterus.
101. Enlarged foramen magnum: a condition in which the opening in the skull where
the vertebral column begins is too large.
102. Enostosis: a bony growth within the hollow part of a bone.

103. Entropion: an abnormal rolling in of the eyelid.
104. Eosinophilic granuloma: an allergic reactive syndrome characterized by the
plaque-like accumulation of eosinophils, a type of white blood cell.
105. Eosinophilic panosteitis: a painful inflammatory bone disease of young, rapidly
growing dogs, often characterized by increased eosinophils in the blood. (also see
#231.)
106. Epidermal dysplasia: abnormal development of the outer layer of the skin.
Common in the West Highland White Terrier and begins in as a puppy. (also see #331.)
107. Epidermoid cyst: a small growth consisting of tissues of the outer layer of the
skin. (also see #274.)
108. Epidermolysis bullosa: an abnormal looseness to the skin characterized by large,
deep, blister-like lesions.
109. Epilepsy: a disease characterized by convulsions (seizures) and/or disturbances
of consciousness.
110. Epiphora: abnormal draining of tears often due to overproduction.
111. Epiphyseal dysplasia: abnormal development of the epiphysis, a part of the long
bones.
112. Esophageal achalasia: a functional stricture or spasm of the muscles of the
esophagus where it joins the stomach.
113. Esophageal dilatation: an abnormally large and usually flaccid esophagus.
114. Eversion of nictitating membrane: a condition where the third eyelid is
protruding.
114a. Exercise-induced collapse: seen in Cavalier King Charles Spaniel puppies
associated with exercise- or excitement-induced muscle hypertonicity (similar to startle
disease in people). *Also seen in young adult field trial Labrador Retrievers.
115. Eye abnormality: any of a number of problems with the eye.
116. Facial fold dermatitis: an infection of the facial skin caused by unusual or
excessive skin folds (seen in dogs such as the Pekingese or Chinese Shar-Pei).
117. Facial nerve paralysis: a decrease or cessation of function of the facial nerve
leading to a drooping of the affected side of the face.
118. Factor I deficiency or hypofibrinogenemia: a rare deficiency of a clotting factor
(fibrinogen), which causes excessive bleeding.
119. Factor II deficiency or hypoprothrombinemia: a rare deficiency of prothrombin,
a clotting factor needed to control bleeding.
120. Factor VII deficiency: a mild bleeding disease primarily of Beagle dogs.
121. Factor VIII deficiency or hemophilia A: the most common severe inherited
clotting disorder of humans and animals. The disorder is inherited as a sex-linked
recessive trait (carried by females and manifested in males). Affects most dog breeds.
122. Factor IX deficiency or hemophilia B: same as hemophilia A, but rarer and
involves a different clotting factor.
123. Factor X deficiency: a rare clotting disorder primarily of the American Cocker
Spaniel and an autosomal trait (affects both sexes).
124. Factor XI deficiency: a rare clotting disorder; protracted bleeding from surgical
procedures is a feature. Both sexes are affected.

124a. Factor XII deficiency: a clotting factor deficiency that rarely produces clinical
signs, which is usually diagnosed incidentally during blood testing for potential bleeding
disorder. *Toy and Standard poodle, and occasionally in other breeds
124b. Familial amaurotic idiocy: deposits of fatty pigments in the brain produce loss of
vision, stupor, and seizures. *English Setter, German Shorthaired Pointer and
Australian Cattle Dog
(also see #177, 193a, 214.)
124c. Fanconi syndrome: a kidney tubular dysfunction of the Basenji which leads to
glycosuria. (also see #268.)
124d. Femoral artery occlusion: a rather common disorder of genetic predisposition
and probable weakness in the femoral artery wall of the Cavalier King Charles Spaniel
125. Fibrosarcoma: a cancer arising from certain types of fibrous cells.
126. Fibrous histiocytoma: a type of fibrous tumor arising from cells called histiocytes.
127. Flank sucking: a behavioral problem common in the Doberman Pinscher and
exhibited as a continually wet patch on the flank (from sucking the skin).
128. Fold dermatitis: an inflammation of skin folds especially in dogs with loose skin
(e.g., Chinese Shar-Pei).
128a. Follicular dysplasia: malformation of skin follicules.
129. Folliculitis: an infection of the hair follicles.
129a. Fragmented coronoid process: osteochondrosis of the elbow joint. (also see
#221a.)
129b. Fucosidosis: an autosomal recessive, fatal disease caused by deficiency of
alpha-fucosidase enzyme resulting in accumulation of fucose-containing metabolites in
cells throughout the body. Neurologic signs predominate. *English Springer Spaniel
(also see #193a.)
130. Furunculosis: an infection of the deeper structures of the skin.
131. Gastric torsion: a condition where the stomach twists, thereby impeding input and
output. (also see #31.)
132. Generalized myopathy: a condition affecting all the muscles of the body which
produces weakness.
133. Genu valgum: malformation of the knee joint ("knock-kneed").
134. Gingival hyperplasia: overgrowth of the gum tissues.
135. Glaucoma: abnormally high pressure in the eye.
136. Globoid cell leukodystrophy: abnormal development and/or function of certain
types of white globoid cells in the brain. (also see #193a.)
136a. Gluten-sensitive enteropathy: also called wheat-sensitive enteropathy of the
Irish Setter. Intolerance to foods containing glutens, affected dogs primarily have
chronic diarrhea and weight loss. (also see #258a.)
137. Glycogen storage disease: characterized by an inability to store and utilize
carbohydrates. (also see #193a.)
138. Goiter: a swelling of the thyroid gland.
138a. Granulocyte dysfunction or adhesion defect: an impairment of neutrophil
function or adhesion which causes chronic recurring infections, stunted growth and
secondary increase in immune globulins (hypergammaglobulinemia). *Irish Setter and
Doberman Pinscher

139. Granulomatous colitis: a type of chronic inflammation of the colon characterized
by reactive tissue growths.
140. Granulomatous sebaceous adenitis: a disease of sebaceous (sweat) skin glands
characterized by reactive tissue growth and autoimmune destruction of the sebaceous
glands. Hair loss occurs and is poorly responsive to treatment. *Standard Poodle,
Akita, Samoyed and Vizsla
141. Hair follicle tumors: abnormal growths of the hair follicles.

142. Hairlessness: also called alopecia or loss of hair.
[edit: [balding; Demodicosis or Demodex-mange in puphood can cause follicular
scarring & a characteristic pattern of bald rings round the eyes, thinning on the forechest
to either side near the upper arms, on the flank & groin, & behind the axillae/armpits.]

143. Hanging tongue: a syndrome where the tongue does not retract into the mouth
properly, due to neurologic or anatomic defects. *Cavalier King Charles Spaniel
143a. Hemangiosarcoma: a cancer of blood vessels involving liver, spleen or skin.
144. Hemeralopia: inability to see in daylight.
144a. Hemorrhagic gastroenteritis: an acute disorder characterized by bloody
diarrhea, elevated hematocrit and shock. *Miniature Schnauzer
145. Hemivertebra: a particular kind of malformation of the vertebra where only half of
the structure is formed.
146. Hemolytic anemia: anemia caused by the destruction of the red blood cells by an
autoimmune process. *Cocker Spaniel and Old English Sheepdogs, as well as several
other breeds.
147. Hemophilia A: a blood clotting disorder due to deficiency of coagulation factor VIII
(this is the most common type of hemophilia in dogs). (also see #121.)
148. Hemophilia B: a blood clotting disorder due to lack of coagulation factor IX. (also
see #122.)
149. Hepatic portosystemic shunt or arteriovenous fistula: a malformation of blood
vessels in the liver or an abnormal communication between the arteries and veins in the
liver.
149a. Hepatic lipidosis: an abnormal accumulation of lipids in the liver which leads to
liver failure. *Miniature Schnauzer and Shetland Sheepdog
149b. Hereditary nephritis: also called “Samoyed hereditary glomerulopathy,” a sex-
linked disease of young males. Affected dogs have renal glomerular disease which
rapidly progresses to kidney failure and death. Female carriers have abnormal
glomerular basement membrane, as well, but usually remain healthy until later in life
when renal failure may occur.
149c. Hereditary spinal muscular atrophy: an autosomal dominant degenerative
disease of motor neurons characterized by weakness and muscle atrophy with a typical
gait, and progressing to dangling of the head and a drooping, paralyzed tail. Severely
affected dogs become paralyzed and die by 3-4 months of age. *Brittany Spaniel
149d. Hepatocerebellar degeneration: a syndrome of progressive cerebellar and
hepatic disease of 6-8-week-old Bernese Mountain Dogs with lesions of cerebellar
abiotrophy and coexistent hepatic lesions. Autosomal recessive inheritance.
150. Hermaphroditism: a syndrome where the individual has anatomical features of
both sexes.
151. Heterochromia, iris: the presence of different colors in the same or both irises.
152. Hip dysplasia: a developmental malformation or subluxation of the hip joints.
153. Histiocytoma: a common benign tumor of certain skin tissue cells (i.e.,
histiocytes).

153a. Histiocytosis: the most prevalent cancer of Bernese Mountain Dogs, usually
leading to early death.
154. Hydrocephalus: a condition where there is an abnormal accumulation of fluid in
the ventricles of the brain.
155. Hygroma: a fluid-filled sac usually occurring on the elbows of large breed dogs
such as the Great Dane or Irish Wolfhound.
156. Hyperadrenocorticism or Cushing's disease: a disease where the adrenal
glands are overactive. (also see #71.)
157. Hypercholesterolemia: a disease where the animal has too much cholesterol in
the blood system. This is commonly associated with hypothyroidism.
157a. Hyperkalemia: a benign condition of large Japanese dog breeds (Akita, Shiba
Inu, Tosu Inu) in which the red blood cell membrane has an altered metabolism and
leaks potassium into the serum making concentrations very high. The condition is
aggravated by ingesting onions.
157b. Hyperlipidemia: an idiopathic disorder of the Miniature Schnauzer in which blood
lipid levels become very high and predispose to pancreatitis. (also see #149a.)
157c. Hyperphosphatasemia: a benign familial condition in humans and the Siberian
Husky in which serum alkaline phosphatase concentrations are very high.
157d. Hypertrophic neuropathy:
a form of polyneuropathy seen in the Tibetan Terrier (also see #250a.)
158. Hypertrophic osteodystrophy: a condition of rapidly growing giant breeds where there is an abnormal inflammation of bones with pain and development of excessive bony growths.
159. Hypertrophy of membrana nictitans gland: a condition where the gland of the third eyelid is abnormally large.
159a. Hypoadrenocorticism: autoimmune or other causes of destruction of the adrenal glands produces a deficiency of corticosteroids. (also see
#9a.)
160. Hypoglycemia: abnormally low blood glucose levels.
160a. Hypomyelinogenesis: failure of the nervous system to form myelin, seen at birth.

Last edited by leashedForLife; 29-06-2011 at 02:10 AM.. Reason: add a personal note to 142, Hairlessness/hair-loss
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  #72 (permalink)  
Old 28-06-2011, 04:51 PM
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Lightbulb AVAR's Guide to Congenital & Heritable Disorders in Dogs

continuing from condition / disorder #161 -
Quote:
161. Hypopigmentation, lips and nose: a condition where an animal lacks pigment
(color) in areas where it is usually present. (also see #328.)
162. Hypoplasia of dens: a condition where part of the second vertebra fails to develop
fully and leads to instability.
163. Hypoplasia of larynx: a condition where the larynx (cartilage of the "voice box")
fails to develop fully.
164. Hypoplasia of trachea: a trachea that fails to develop fully.
165. Hyposomatotropism: failure of the body growth hormones
(somatomedins) to develop fully. This is also known as growth hormone responsive
dermatosis. *Pomeranian
166. Hypothyroidism: a common endocrine disease where the body produces an
abnormally low amount of thyroid hormones. This is an autoimmune destruction of the
thyroid gland which affects more than 50 dog breeds. (also see #192, 312.)

167. Hypotrichosis: a condition where there is an abnormally small amount of hair
growth.
168. Immunoglobulin A deficiency: a condition where concentrations of secretory
immune globulins are low. *Chinese Shar-Pei and Beagle (also see #187.)
169. Immunoglobulin G deficiency: a condition where circulating antibody
concentrations are low, which produces immune deficiency and susceptibility to
infections.
170. Immunoglobulin M deficiency: a condition where antibodies produced in early
stages of an immune response are low, producing susceptibility to infection. *Doberman
pinscher
171. Inguinal hernia: a break in the muscular layer of the body wall occurring at the
inguinal canal (where the back leg meets the body).
171a. Inherited ventricular tachycardia: a condition of young German Shepherds with
very rapid heart rates, ventricular arrhythmias, and sudden death.
172. Intestinal malabsorption: a disease where the intestinal tract does not absorb
nutrients properly. This is also known as protein-losing enteropathy as a consequence
of inflammatory bowel disease. In Irish Setters, there is also a wheat-sensitive
enteropathy.
173. Intervertebral disc disease: a disease where the discs between the vertebrae are
abnormal and prone to rupture and misplacement.
174. Intussusception: a serious condition where the intestinal tract telescopes in on
itself.
175. Iris atrophy: a condition where the iris (the colored part of the eye) shrinks and
becomes non-functional.
176. Iris heterochromia: a condition where one iris is a different color from the other or
has more than one color to it.
176a. Ivermectin sensitivity: a prevalent condition of the Collie where a mutation of
the MDRI gene produces susceptibility to ivermectin toxicity.
177. Juvenile amaurotic idiocy: a syndrome characterized by early onset blindness
and low mental capacity.
178. Juvenile cellulitis: an inflammation of cells (usually skin cells) occurring in the
young animal.
178a. Juvenile polyarthritis: a form of arthritis affecting multiple joints of young Akitas,
and usually occurring within 1-4 weeks of vaccination. Cases typically occur at 3-4
months of age after the second or subsequent booster vaccination and respond poorly
to therapy. Affected dogs may progress to develop amyloidosis (#11) and renal failure.
179. Keratitis sicca: a condition where one or both eyes do not produce a normal
amount or type of tears.
180. Keratoacanthoma: a small growth, usually on the face, filled with keratin material.
181. Keratoconjunctivitis sicca: (See #179.)
182. Kidney aplasia, unilateral: a developmental abnormality where one kidney fails to
develop, also called renal agenesis.
183. Kinked tail: a developmental abnormality where the tail has a pronounced kink.
184. Lacrimal duct atresia: a condition where the duct draining tears from the eye is
too small or not formed.

184a. Laryngeal paralysis: a progressive paralysis of the larynx of young Bouvier des
Flandres, Siberian Huskies, and Dalmatians. In the Dalmatian, the condition is usually
linked to polyneuropathy (#250a). Affected dogs have an unusual bark and are prone to
aspiration pneumonia.
185. Legg-Perthes disease: disease in which the blood vessels feeding the femoral
head (top part of the thigh bone) shrink, leading to starvation and death of the femoral
head (the ball of the ball-and-socket joint of the hip). Also called Legg-Calve'-Perthes
disease.
186. Lens luxation: a condition where the lens in the eye is displaced into an abnormal
position.
187. Linear IgA dermatosis: a type of skin disease resulting from an abnormality of the
secretory immune system. *Chinese Shar-Pei
188. Lip fold dermatitis: a skin infection caused by redundant skin folds around the
mouth.
188a. Lipidosis: a form of lysosomal ‘storage’ disease where lipids accumulate in
nerves. Called GM-1 gangliosidosis in the Portuguese Water Dog (also see #193a.)
189. Lissencephaly: an abnormal brain development where the surface lacks gyri (the
grooves).
190. Lung torsion: a condition where one or more lung lobes twist upon themselves.
190a. Lupoid onchodystrophy: (also see #218a.)
191. Lymphedema: a disorder where valvular blockage of lymph flow or twisted
lymphatic ducts causes an accumulation of fluid to swell tissues with edema.
192. Lymphocytic thyroiditis: an autoimmune disease causing inflammation and
destruction of the thyroid gland, which becomes infiltrated with lymphocytes (white
blood cells) and leads to hypothyroidism. This is the most common endocrine disease of
the dog and has an inherited predisposition. (also see #166, 312.)
193. Lymphosarcoma: a cancerous condition involving the lymphatic system. This is
one of the more common canine cancers.
193a. Lysosomal ‘storage’ diseases: a group of progressive multifocal neurologic
disorders caused by specific enzyme deficiencies leading to death of nerve cells and
accumulation of their respective enzyme substrates in cells. (also see #299a.)
194. Malabsorption syndrome: (See #172.)
194a. Malignant histiocytosis: the more aggressive, rapidly fatal systemic form of
histiocytosis. Heritable in the Bernese Mountain Dog, with no cure. (also see #153a.)
194b. Malignant hyperthermia: an autosomal dominant trait of the black Labrador
Retriever. Very high body temperatures develop in response to gaseous anesthesia.
195. Malocclusion: a condition where the teeth do not meet properly.
196. Mastocytoma: a rare cancer developing from a type of tissue cell known as a
mast cell.
197. Melanoma: a rare cancer developing from the type of skin cell which produces
pigment (melanin).
197a. “Merle” eye anomaly: (also see #52, 58.) The breeding of two merle colored
parents can produce some offspring with whiter coat color. These puppies typically
inherit a variety of anomalies of the back (fundus) of the eye, which can be confused
with choroidal hypoplasia.

198. Metabolic bone disease: any of a number of diseases affecting the bones due to
an abnormality of metabolism.
199. Microphthalmia: a condition where one or both eyes are too small.
199a. Microvascular dysplasia: (See #252a.)

200. Missing teeth:
too few teeth. [EDIT: several hairless breeds are missing teeth in the hairless
versions, while powderpuff dogs have full mouths; breeding hairless to hairless is a
fatal factor in these breeds, so hairless must be bred to haired dogs.
The American Hairless Terrier, a sport of the Rat Terrier, lacks the fatal factor & the dogs
are full-mouthed.]

201. Mitral valve defects: a group of abnormalities of the mitral valve of the heart.
202. Mononephrosis: a condition where only one kidney is present.
202a. Mucinosis: a common skin disorder of the Chinese Shar-Pei characterized by
generalized pitting edematous folds, variable itching, and severe puffiness and wrinkling
of the head and extremities. Vesicles may be present and rupture draining clear, stringy
fluid. This is often associated with hypothyroidism and IgA deficiency. (also see #166,
168.)
202b. Mucopolysaccharidosis: an inborn metabolic error of several types leading to
storage disease and debilitation. *Schipperke (type IIIb or Sanfilippo syndrome)
*Miniature Pinscher (type VI) *German Shepherd (type VII). (also see #299a.)
203. Multiple colobomas: a developmental abnormality of the structures of the eye.
204. Multiple epiphyseal dysplasia: a condition where many of the long bones
develop abnormally due to changes in the growth plates.
204a. Muscular dystrophy: a congenital and often inherited form of generalized
muscle dysfunction which causes signs such as poor growth, weakness, abnormal gait,
difficulty eating and swallowing, and muscle atrophy. Affected animals have serious
health problems and may die or be euthanatized. Inheritance is sex-linked in the Golden
Retriever, Irish Terrier, Samoyed and Belgian Shepherd.
205. Muzzle pyoderma: an infectious skin disease on the muzzle of an animal.
206. Myasthenia gravis: a syndrome characterized by muscle fatigue due to an
autoimmune disease which produces chemical abnormalities of the muscles and
nerves. An enlarged esophagus called megaesophagus can result and causes
regurgitation of food.
206a.Myotonia congenita: a condition present at birth characterized by tonic muscle
contractions and twitching. *Miniature Schnauzer
206b. Narcolepsy: a neurological disorder characterized by falling asleep suddenly
(collapse) which can occur during periods of activity and last for various lengths of time.
*Doberman Pinscher and Labrador Retriever
207. Narrow palpebral fissure: an abnormally small opening between the upper and
lower eyelids.
208. Nasal pyoderma: a skin infection of the nose.
209. Nasal solar dermatitis: a skin disease of the nose and muzzle which is greatly
affected by exposure to sunlight. *Collie
210. Nasolacrimal puncta atresia: (See #23.)
211. Necrotizing myelopathy: a condition where the spinal cord gradually dies.
212. Necrotizing panotitis: a severe infection of the ear and surrounding tissues.
213. Neuromuscular atrophy: a condition where the muscles waste away due to lack
of proper nerve supply.
214. Neuronal ceroid lipofuscinosis: a congenital disease where fatty pigments are
deposited in the brain and cause brain dysfunction. (also see #193a.)

215. Neurotropic osteopathy: a disease of the bones due to abnormalities of the
nerves.
216. Nodular panniculitis: a skin disease characterized by nodules of inflammation
under the skin.
217. Oligodendroglioma: a cancer arising from a type of cell found in the brain and
spinal cord.
218. Oligodontia: an abnormally small number of teeth.
218a. Onchodystrophy: painful symmetrical nail bed disorder causing the nails to fall
off; cause unknown. *Greyhound, Rottweilers and several other breeds. (also see
#190a.)
219. Open fontanel: a condition where the suture lines between bones of the skull do
not fuse together properly.
220. Optic nerve hypoplasia: a condition where the optic nerve going from the eye to
the brain is too small.
221. Osteochondritis dissecans: a specific form of inflammation of the cartilage of
certain joints which causes arthritis. (alsos ee #221a.)
221a. Osteochondrosis: a group of developmental diseases resulting in abnormal
formulation of joint cartilage. Commonly involves the shoulder, stifle, hock or elbow.
(also see #221.)
222. Osteodystrophy: any of a number of diseases involving the development of the
bones.
223. Osteogenesis imperfecta: imperfect development of the structure and/or
mineralization of the bones.
224. Osteopetrosis: a condition where the bones are abnormally dense and hard.
225. Osteosarcoma: a cancer arising from the cells of the bones.
226. Otitis externa: an infection of the external structures of the ear.
227. Otocephalic syndrome: a developmental abnormality where the animal lacks a
lower jaw and the ears meet below the face.
228. Overshot jaw: a condition where the upper jaw is too long for the lower jaw.
229. Pancreatic insufficiency: a condition where the pancreas does not produce the
proper enzymes for digesting food.
230. Pannus: an immunologic eye disease characterized by abnormal growth of tissue
over the cornea.
231. Panosteitis: (See #105.)
232. Parosteitis: inflammation of tissue around a bone.
233. Parotitis: inflammation of the parotid salivary gland, also called parotiditis.
234. Partial alopecia: some loss of the normal hair coat.
235. Patella luxation: a condition where the knee caps slide in and out of place.
236. Patent ductus arteriosus: failure of the vessel remnant joining the aorta and
pulmonary artery in fetal life to close properly at birth, thereby shunting blood away from
the lungs.
237. Pattern alopecia or baldness: hair loss occurring in certain patterns. *Dachshund
238. Pemphigus erythematosus: one of many skin diseases caused by an
autoimmune mechanism.
239. Pemphigus foliaceous: another skin disease caused by autoimmune destruction
of tissues.

240. Perianal adenoma: a cancer arising from a cell of a gland found near the anus.

Last edited by leashedForLife; 29-06-2011 at 04:16 AM.. Reason: add note to #200
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AVAR's Guide to Congenital & Heritable Disorders in Dogs

continuing from condition / disorder #240 -
Quote:
241. Perianal fistulas: a condition characterized by abnormal communications from
deeper tissues to the skin surrounding the anus.
242. Perianal gland tumor: (See #240.)
242a. Peripheral sensory neuropathy: a disorder of young puppies born without pain
sensation of peripheral tissues. (also see #8.)
243. Persistent right aortic arch: a developmental abnormality where one of the fetal
blood vessels near the heart does not atrophy as it should.
244. Persistent hyaloid artery: as #243, however, involving a blood vessel inside the
eye.
245. Persistent pupillary membrane: a developmental abnormality where the
membrane forming the iris does not form properly.
245a. Phosphofructokinase deficiency: a deficiency of a specific red blood cell
enzyme in the English Springer Spaniel. Causes chronic anemia, exercise-induced
acute hemolytic crises and enlarged spleen.
245b. Physiologic leukopenia: a condition of most healthy adult Belgian Terverun
whereby the total white blood cell count (neutrophils, lymphocytes, and monocytes) is
below 6,000/ul. Because of their ancestral relationship to the other Belgian Shepherd
dogs (Belgian Sheepdog and Belgian Malinois), these breed/varieties may also show
the same phenomenon.
246. Pigmentary keratitis: an inflammatory condition of the cornea characterized by
abnormal pigmentation.
247. Pituitary dwarfism: a developmental abnormality resulting in an undersized
animal due to a defective pituitary gland.
248. Pituitary tumor: a cancer arising from the pituitary gland.
249. Platelet disorder: a group of abnormalities of small blood cells necessary to
control bleeding. (also see #311, 311a.)
250. Pododermatitis: a skin infection of the paws.
250a. Polycystic kidney disease: malformation of kidneys where the renal pelvis is
cystic. This disease may be associated with heart valvular disease in the Bull Terrier.
250ba. Polyneuropathy: a progressive polyneuropathy of young dogs leading to
neuromuscular atrophy, variable demyelination, paraparesis, exercise intolerance and
hyperesthesia. *Alaskan Malamute, Dalmatian, Golden Retriever, Rottweiler and
German Shepherd (also see #213.)
251. Polyostotic fibrous dysplasia: a type of bone disease where the bones are
composed of improper fibrous tissues.
252. Polyradiculoneuritis: an acute inflammatory disease of several groups of nerves
causing fever.
252a. Portosystemic shunt: a congenital anomaly of blood vessels supplying the liver,
causing varying degrees of liver dysfunction or failure. This condition can also be
manifested as microvascular dysplasia. *Yorkshire and Cairn Terrier, but can occur in
any breed. (also see #149, 199a.)
253. Posterior retinal atrophy: a deterioration of the part of the eye which translates
light to electric impulses (the retina) and produces night blindness. (also see #256.)

253a. Primary hyperparathyroidism: overactive production of parathyroid hormone,
most often caused by parathyroid gland tumor, and leading to renal failure from
secondary hypercalcemia. *Keeshond
254. Primary peripheral retinal dystrophy: a certain type of developmental disease
affecting the retina.
255. Progressive ataxia: a condition where the animal's sense of coordination
deteriorates.
256. Progressive retinal atrophy: a disease where the retina slowly deteriorates,
producing night blindness.
257. Prolapsed rectum: a condition where the inside of the rectum protrudes outside
the anus.
258. Prolapsed uterus: a condition where the uterus protrudes into the vaginal canal or
through the vaginal opening.
258a. Protein-losing enteropathy: a relatively common genetically predisposed
condition also called inflammatory bowel disease. Vomiting, diarrhea, and weight loss
are the common signs. *Seen in many breeds, but mostly in Soft Coated Wheaten
Terrier (in conjunction with #258b), Rottweiler, Bernese Mountain Dog, German
Shepherd, Golden Retriever, Dalmatian, Akita, Irish Setter and English Setter
258b. Protein-losing nephropathy: a condition where protein is lost through the
kidney. Affected dogs have excessive thirst and urination, which progresses to
peripheral edema and renal failure. *Soft Coated Wheaten Terrier (in conjunction with
#258a).
259. Pseudohermaphrodism (pseudohermaphroditism): a condition where the
animal has the gonads of one sex, but the appearance is ambiguous or is of the
opposite sex.
260. Pulmonic stenosis: a condition where one of the valves of the heart does not
open properly.
261. Pyloric stenosis: a condition where the opening leading from the stomach does
not function properly.
262. Pyometra: a bacterial infection of the uterus where it fills with pus.
263. Pyruvate kinase deficiency: a deficiency of a specific red blood cell enzyme.
*Basenji, Beagle and Cairn Terrier
264. Quadriplegia with amblyopia: a syndrome characterized by weakness of all four
limbs, as well as of vision.
264a. Rage syndrome: sudden unprovoked aggression of serious nature. *English
Springer Spaniel (also see #27.)
265. Recessive retinal dysplasia: a developmental disorder resulting in an abnormal
retina, carried by a recessive gene.
266. Renal cortical hypoplasia: a condition where the cortex of the kidney(s) develops
incompletely.
266a. Renal dysplasia: a condition where the kidneys form abnormally. Renal failure
develops with protein loss in urine.
267. Renal hypoplasia: a condition where the kidney(s) do not develop completely.
268. Renal tubular dysfunction: a condition where the tubules of the kidneys (the
filtering structures) do not function properly. (also see #124c.) *In the Basenji, glycosuria
develops and is called Fanconi syndrome.

269. Retinal detachment: where the retina is unattached to the back of the eye.
270. Retinal dysplasia: a condition where the retina is malformed.
271. Schnauzer comedo syndrome: a skin disease of schnauzers where the skin
forms comedones ("blackheads").
272. Scotty cramp: a condition found in the Scottish Terrier where the animal has
periodic, generalized cramping of the muscles.
273. Screw tail: a birth defect where the tail is twisted tightly on itself.
273a. Sebaceous adenitis: (See #140.)
274. Sebaceous cyst: a small mass in the skin with a secretory lining and filled with a
yellow waxy-like material. (also see #107.)
275. Sebaceous gland tumor: a tumor arising from sebaceous glands of the skin.
276. Seborrhea: a skin disease with excess scaling of the skin and often an excess of
sebum (oil-like substance) and odor.
277. Sertoli cell tumor: a tumor of the testicles which secretes estrogen and causes
feminization.
277a. Shar-Pei fever syndrome: similar to familial Mediterranean fever of humans,
affected Shar-Pei have waxing and waning high fevers, and swelling of the tarsus joints
(swollen hock syndrome), which can progress to renal or hepatic amyloidosis.
278. Short skull: a skull that is abnormally short for the breed in question.
279. Short spine: a spine that is abnormally short for the breed in question.
280. Short tail: a tail that is abnormally short for the breed in question.
281. Shoulder abnormalities: a group of disorders of the shoulder joint due to
malformation or subluxation.
282. Shoulder dysplasia: a looseness of the shoulder joint.
283. Silica uroliths: stones which are composed primarily from silicone that forms in
the bladder.
284. Sinoatrial syncope: a condition where the electrical impulses of the heart are
abnormal and the animal has episodes of syncope (fainting).
285. Skin disorders: any of a number of abnormalities of the skin.
286. Skin neoplasms: any number of tumors arising from cells of the skin.
286a. Soft tissue cancers: prevalent and inherited in the Flat Coated Retriever.
287. Spina bifida: a developmental abnormality where some vertebra are malformed
thereby exposing the spinal cord.
288. Spinal cord demyelination (ataxia): an abnormality of the nervous tissue of the
spinal cord leading to incoordination.
289. Spinal dysraphism: a developmental abnormality where the spinal cord does not
form completely. (also see #305.)
290. Spinal osteochondrosis: a specific type of developmental abnormality of the
vertebrae.
290a. Spinal process (vertebral) malformation: (See #61c.)
291. Splenic torsion: a condition where the spleen twists upon itself.
292. Spondylolisthesis (Wobbler's syndrome): a condition where the vertebrae of the
neck slip out of joint and are malformed causing progressive incoordination of the rear
legs. *Doberman Pinscher (also see #51, 332.)
293. Spondylosis: a malformation of the vertebrae.
294. Squamous cell carcinoma: a cancer arising from the squamous type of skin cell.

295. Stenotic nares: a condition where the openings of the nose (nares) are too small.
296. Sterile pyogranuloma syndrome: a disease of the deeper layers of the skin
characterized by formation of abnormal tissues, with no infectious organisms involved.
297. Sternal callus: a thickened, hairless area forming on the chest of an animal.
298. Stockard's paralysis: a degeneration of parts of the spinal cord causing paralysis.
299. Stomach torsion: (See #131.)
299a. Stomatocytosis: disorder where red blood cells have a mouth-like shape leading
to frequent bouts of hemolytic anemia, and increased red cell osmotic fragility. (also see
#13.)
299b. ‘Storage’ disease: (See #193a, 188a.)
300. Subaortic stenosis: a tightening of the outflow opening for blood to go from the
heart into the aorta. *Golden Retriever and Newfoundland
301. Subcorneal pustular dermatosis: a skin inflammation occurring between certain
layers of the skin.
302. Subcutaneous cysts: small fluid-filled masses accumulating under the skin.
303. Subvalvular aortic stenosis: as #300, but the tightening occurs below the aortic
valve.
303a. Sulfonamide sensitivity: a condition in genetically predisposed breeds where
metabolism of potentiated sulfonamides is impaired and adverse side-effects are seen,
including liver dysfunction, dry eye (#181), rheumatoid arthritis and bone marrow failure
(red blood cell and/or platelet destruction). *Doberman Pinscher, Samoyed, American
Eskimo, Kuvasz and Great Pyrenees
304. Swimmer puppies: a developmental defect which causes a flattening of the body
so that newborn pups are unable to place their feet under them for proper locomotion.
304a. Syncope: a brief period of fainting or collapse. (also see #206a.)
305. Syringomyelia: developmental abnormalities causing cavities within the spinal
cord, probably just an effect of #289. *Rhodesian Ridgeback
306. Systemic lupus erythematosus: an autoimmune disease where antibodies form
against the nuclear protein of cells, characterized by skin lesions as well as other organ
dysfunctions and blood abnormalities.
307. Tail abnormalities: any number of problems associated with the tail.
308. Tail fold dermatitis: a skin infection caused by abnormal tissue folds around the
tail.
308a. Taurine-deficient cardiomyopathy: a reversible dilated cardiomyopathy caused
by taurine deficiency in the Golden Retriever and Newfoundland. (also see #38.)
309. Teeth abnormalities: any number of problems of the teeth.
310. Tetralogy of Fallot: a specific four-way developmental abnormality of the
structures of the heart and associated great vessels.
311. Thrombocytopathy: a functional abnormality of small blood cells (thrombocytes or
platelets) which are needed to control bleeding. (also see #249.)
311a. Thrombocytopenia: a reduced number of platelets in the blood which causes
pinpoint hemorrhages in the skin and mucosa and often accompanies #146 as an
autoimmune syndrome called Evans syndrome. (also see #249.) *Cavalier King Charles
and English Toy Spaniel (mild to moderately severe familial thrombocytopenia can be
an incidental finding in clinically normal animals).

311b. Thymic atrophy: a deficiency of cell-mediated immunity expressed by decreased
T-cell function and low concentrations of growth hormone. *Weimaraner (also see
#165.)
312. Thyroiditis: an autoimmune inflammatory disease of the thyroid gland. (also see
#166, 192.)
313. Tracheal collapse: (See #57.)
313a. Transitional cell carcinoma: a form of bladder cancer especially common in the
Scottish Terrier and West Highland White Terrier (also see #37.)
314. Trembling of the hindquarters: a condition where the rear legs tremble due to
muscle weakness or other pathologies.
315. Type II muscle fiber deficiency: a deficiency in form and/or function of a specific
type of muscle fiber.
316. Ulcerative colitis: an autoimmune inflammation of the lining of the colon
characterized by formation of ulcers.
317. Ulcerative keratitis: an inflammation of the cornea characterized by the formation
of ulcers.
318. Umbilical hernia: a break in the abdominal muscle wall at the point where the
umbilical cord enters the body.
319. Undershot jaw: a condition where the lower jaw is too long for the upper jaw.
320. Ununited anconeal process: a developmental abnormality of one of the bones of
the elbow joint causing pain. (also see #221a.)
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Old 28-06-2011, 04:56 PM
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Lightbulb AVAR's Guide to Congenital & Heritable Disorders in Dogs

continuing from condition / disorder #320 - last batch
Quote:
321. Uric acid calculi: bladder stones which are formed primarily from urates.
*Dalmatian
322. Uric acid excretion abnormalities: an abnormality in the process of the excretion
of the uric acid formed during metabolism. *Dalmatian
322a. Urolithiasis: stone formation in the urinary tract.
323. Uterine eclampsia: (See #91.)
324. Uterine inertia, primary: a condition where the uterus does not have the muscular
strength to proceed with the birth process, and not due to any acquired problems (e.g.,
malnutrition).
324a. Uveodermatologic syndrome: (See #329.)
325. Vaginal hyperplasia: an overgrowth of tissues of the vagina.
326. Vasculitis: an inflammatory condition of the blood vessels.
327. Ventricular septal defect: an abnormality (usually a hole) in the wall between the
two chambers of the heart.
327a. Ventricular tachycardia: a condition where a ventricle of the heart beats too
rapidly, leading to varying degrees of cardiac irregularity or syncope.
327b. Vitamin B12-responsive malabsorption: a disease of young giant Schnauzer in
which there is selective inability to absorb vitamin B12 from the bowel. Affected puppies
have chronic non-regenerative anemia, low white blood cell counts, low serum vitamin
B12, metabolites (methylmalonic acid) in the urine, and failure to thrive.
328. Vitiligo: a lack of pigment in the skin (called vitiligo in man and hypopigmentation
in animals). *Rottweiler, Doberman Pinscher, Old English Sheepdog and Dachshund
(also see #161.)

329. Vogt-Koyanagi-Harada-like syndrome: an autoimmune disease common in the
Akita and the "sled" dog breeds where the eyes, blood and other tissues are
progressively destroyed leading to blindness and death, also called uveodermatologic
syndrome.
330. von Willebrand's disease: a type of bleeding disorder caused by defective blood
platelet function (an autosomal trait affecting both sexes). *Occurs in 59 dog breeds, but
most often in the Doberman Pinscher
331. Westie armadillo syndrome: a condition of the West Highland White Terrier
where the skin becomes very thickened. This condition is related to atopic (inhalant)
allergies. (also see #106.)
331a. White dog shaker syndrome: a disorder mainly of white dogs having muscular
tremors over entire body, incoordination and rapid eye movements. Episodes occur with
stress or excitement.
332. Wobbler's syndrome: (See #51, 292.)
333. Zinc deficiency: can be caused by dietary problems, but also from an inability to
utilize and store zinc properly and is seen as a lethal problem called acrodermatitis in
the Bull Terrier.
334. Zinc-responsive dermatosis: the skin is abnormal (scaly, hair-loss, etc.) but responds to administration of zinc in the diet.
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Old 14-08-2011, 09:50 PM
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Re: Necessary health tests before breeding

an excellent source of info thanks l4l
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Old 14-08-2011, 10:43 PM
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Arrow AVAR's heritable conditions list

Quote:
Originally Posted by babycham2002 View Post
an excellent source of info thanks l4l
i'm truly sorry that AVAR has disappeared from the Web. they used to have a website.
this list *was* updated regularly, but now i don't think it is - so any new conditions, new tests, etc,
won't be added.

still, it's the best resource that i know of for all breeds in a single document.
thanks to Dr Dodds & her helpers...
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Old 09-09-2011, 11:48 AM
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Re: Necessary health tests before breeding....tresticles genetic issues....

are there any tests for finding if bitches are possible carriers of producing males with only 1 testicle ?

i have read, that this is hereditary and genetic

some say heredity from male others say both bitch and father can carry the problem passed to pups

and if one selected only from dogs with no litter mates with only 1 testicle the problem disappears to reduce from 40 percent amoungst pedigree dogs to around less than 10 percent of mongrel more genetically diverse dogs

sigh

of course breeders do not publish the results of litters as a general rule so hearsay and claims of having dogs ok are not sound

anyone know if there is a test to know if a bitch is a carrier ?

i only recently discovered this. i bought a male pup with 1 testicle. he is now 6 months old no sign of 2nd still

my bitch age 18 months is from litter where 1 male brother had only 1 testicle

so seems to me neither of my dogs is suitable to produce puppies

adding to the problem is that in france in sheepdog herding trials non pedigrees are allowed to take part up to 2 levels and banned from top level even if better and 1 testicle dogs banned also
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Old 09-09-2011, 02:26 PM
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Arrow Re: testes - cryptorchid males, unilateral or bi-lateral

Quote:
Originally Posted by FEJA JUODAS View Post
i bought a male pup with 1 testicle. he is now 6 months old; no sign of 2nd [testis].

my bitch, 18-MO, [had] 1 male brother [with] only 1 testicle.
i don't know if there are any tests; i doubt it, but asking GENE-screening companies or looking
on their websites is a much-more efficient way to find out.

re the unilateral-cryptorchid, Ur male pup:
i'd desex him ASAP. the longer that testis is in the abdomen at internal body-temp,
the greater his risk of carcinogenic changes. He is definitely not breeding quality.


i don't know if a female with a cryptorchid full-brother is likely to carry the trait.
has she passed other gene-screens?
has she had a Penn-HIP or other hip-joint rating?
what about eye-certificate by a k9-opthalmologist?
how good is her pigment, general type, & structure?
does she have a working certificate?
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Old 16-01-2012, 09:33 AM
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Re: Necessary health tests before breeding

I found this page useful when i bred my shih tzu

Shih Tzu Breeder Guidelines
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Re: Necessary health tests before breeding

Basset Hound

Gonioscopy (Glaucoma) once in the life after the age of 12 months
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