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  #81 (permalink)  
Old 21-12-2011, 05:03 PM
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Re: Sick British Shorthair Kitten (4 months Old)

Quote:
Merlins titre test was'nt that high just showed he had been exposed to the virus
I don't think the titre is necessarily high in a kitten with wet FIP. I believe it's often high in dry FIP. The stud having a high count probably meant nothing more than the infection was reasonably recent. We tend to forget when talking about FCoV that for most viral infections a high level of antibodies is a good thing.

What I believe is important to breeders looking to clear it from their households is whether the cat is shedding the virus rather than has a high antibody titre so the RT-PCR test is extremely useful. It's highly important to keep shedders from mixing with the clear cats but a high antibody level from a cat which isn't shedding is not in itself the danger.
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  #82 (permalink)  
Old 21-12-2011, 05:11 PM
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Re: Sick British Shorthair Kitten (4 months Old)

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That's the bit I'd like to follow up the references for. The rest is standard info but I would like to read more on queens passing on an already mutated virus to their kittens. I've never seen anything on this.
That is very worrying
It doesn't fit with anything I've ever read, heard at seminars or with my own observations over the years. Nor does it make sense for the single kitten out of a litter succumbing to FIP when the rest are fine. It does however, account for the author's earlier assertion -
Quote:
for a kitten to have FIP, the mother must have it too, which means she is going to die of it, too
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  #83 (permalink)  
Old 21-12-2011, 05:59 PM
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Re: Sick British Shorthair Kitten (4 months Old)

have just caught up with this subject and am very sorry to hear about your baby boy.
if it helps i do know of someone who sort of runs an advice centre for FIP cat owners and if you need someone to talk to it may help
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Old 21-12-2011, 06:50 PM
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Re: Sick British Shorthair Kitten (4 months Old)

Information from a Dutch veterianry clinic

Quote:
Is FIP wel of niet besmettelijk?
Wanneer in een groep katten FIP optreedt beperkt de ziekte zich vaak tot een enkele kat. Het "FIP"-virus lijkt zich niet gemakkelijk te verspreiden. Het is mogelijk dat het "FIP"-virus, dat door deze kat wordt uitgescheiden, niet meer besmettelijk is voor andere katten. Een andere theorie is dat andere katten wel besmet worden door het "FIP"-virus maar dat zij voldoende bescherming hebben doordat zij antilichamen hebben tegen het onschuldige coronavirus. Er zal in de komende jaren meer onderzoek gedaan moeten worden om meer te weten te komen over FIP.
Translation
Is FIP contageous or not?
When FIP occurs in a clowder of cats, the disease is usually limited to one single cat. Apparently, the 'FIP'virus isn't easily transmitted. It is possible that the FIP virus being spread by this cat is no longer contageous to other cats. An other theroy is that other cats do get infected by the FIP virus, but that their resistance is adequate, due to antibodies against the hharmless corona virus. More research will be necessary in the years to come to gain more knowledge concerning FIP.


Ron Hines DVM PhD has written a long article on FIP and gives another explanation why FIP hardly seems to be transmitted from one cat to another.

Quote:
How Is FIP and Coronavirus Transmitted Between Cats - Where Did My Cat Catch It ?

First off, most veterinarians do not believe that FIP is transmitted between cats. At least we do not believe that it is common for one cat to catch FIP from another. That assumption is based on the fact that FIP-infected cats appear to shed very little virus. Remember, we think that FIP is caused only by a mutated coronavirus. Once the virus mutates, under natural home conditions, it seems to lose its ability to move from one cat to another.

Now that assumption was recently challenged by a group of scientists at the National Cancer Institute. After collecting coronavirus from FIP positive cats in suburban Washington, DC, they came to the conclusion that there existed a strain of wild coronavirus in their area that was much more likely to cause FIP than other strains (a hot strain of virus). (ref). That was a shock to the community that studies feline infectious peritonitis. It did not take long for a second set of scientists in the Netherlands to find major flaws in the NCI study. (ref) . However, the jury is definitely still out as to whether one strain of coronavirus is more likely to cause FIP than another or more likely to result in chronic carrier cats. (ref).

Can My Other Cats Catch FIP From My Sick Kitty?

That probably will not happen. When feline coronavirus looses it’s interest in living in the cats intestine (a change in tropism) and moves deeper into the cats body causing FIP, much less virus is shed in the cat’s feces. Although it is theoretically possible, we just don’t see Much cat-to-cat transmission of coronavirus in its dangerous FIP-form in the real World. Recent studies in the Netherlands confirmed this.(ref) When more than one cat in a household develops FIP, each is likely to have had a mutation event of its own, not transmission from one cat to another.
This may be the study the Dutch vet whose lecture I attended was refering to...

One brochure states that
Quote:
FCoV may possibly be transmitted across the placenta.
The Paw Blog states that
Quote:
One of the commonest scenarios is an infected (but asymptomatic) queen passing on the disease to her kittens.
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Last edited by Jiskefet; 21-12-2011 at 06:53 PM..
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  #85 (permalink)  
Old 26-12-2011, 05:57 AM
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Re: Sick British Shorthair Kitten (4 months Old)

Quote:
One brochure states that
Quote:
FCoV may possibly be transmitted across the placenta.
As far as I'm aware it's accepted that this isn't the case. It was once under question but that was quite some time ago.

Quote:
The Paw Blog states that
Quote:
One of the commonest scenarios is an infected (but asymptomatic) queen passing on the disease to her kittens.
Does this mean FCoV or is this where you found the info claiming a queen will pass on the already mutated virus to her kittens? It is this claim which is new to many (most) of us and why a reference to the academic source would be of great interest.
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