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Old 28-02-2011, 05:07 PM
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Hyperthyroid

Nellie is nearly 17 and has been on Felimazole for around 3 years now, last T4 was in Dec and her levels were well in range. However, she has lost weight and condition over the last months ( even prior to last check up ) She eats fairly well, always asking for food but only having small snacks each time. When I pick her up I can feel her heart seems to be racing faster than it should be.
Obviously I will take her to the vet for a check over...but what are my options in a situation like this?
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Old 28-02-2011, 07:06 PM
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Re: Hyperthyroid

Hi PP,

So which one is Nellie then? Now I see this little gang in front of me! Firstly well done in being able to control the hypert with meds for three years-not many can! Has the weight loss commenced since last T4 test in which case it might now be higher and could also account for the increased heart rate?

Did they just do a T4 test in Dec? If not did the bloodwork show anything outside of range? Apart from a raised T4, the only other thing that springs to mind is she may have some malabsorption problems. How are stools? Any vomiting?

Theoretically the heart rate should have decreased now the T4 is in range. Has the commented on this if present on last check?

All this is quite interesting because recently I read somewhere ( think it was Idexx lab report ) where cobalamin ( Vitamin B12 ) and folate has been found to be lower in hyperthyroid cats-I believe even when it's controlled. I know that when B12 is supplemented it aids weight gain. I've noticed this with my IBD cat though diet in his case also helped in combating the malabsorption problems which were responsible for his weight loss. Also a specific blood test revealed he had these deficiencies ie cobalamin though folate was raised.

I wonder therefore if you might see a difference after some B12 injections. Do speak to the vet of course about this. At any rate being water soluble any excess is excreted so it won't do any harm. Think you can also buy it online without a prescription-I used methylcobalamin in my case.

There is a chance also this may be a feature of the long term use of Felimazole-I've only used it preoperatively! Are you a member of the Yahoo group? They might have some more insight into this considering a lot of members there are very experienced in treating the conditon quite often in combination with others as well!

Last edited by Ianthi; 28-02-2011 at 11:20 PM.. Reason: typos
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Old 28-02-2011, 07:27 PM
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Re: Hyperthyroid

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Originally Posted by Ianthi View Post
Hi PP,

So which one is Nellie then? Now I see this little gang in front of me! Firstly well done in being able to control the hypert with meds for three years-not many can! Has the weight loss commenced since last T4 test in which case it might now be higher and could also account for the increased heart rate?
Nellie is the one furthest on the right. I am pretty strict about getting her pills into her....still some days she evades me! The weight loss is fairly minimal, but there is a loss of muscle mass I feel, her back bone is prominent and her coat looks scruffy again.I think this was going on even before last check up

Did they just do a T4 test in Dec? If not did the bloodwork show anything outside of range? Apart from a raised T4, the only other thing that springs to mind is she may have some malabsorbtion problems. How are stools? Any vomiting?
Full bloods were taken, I think one slightly raised value so I asked for spec FPL1 which was negative. One of them had been passing very pale stool in the garden, last time I saw her stool this week it looked fine, very stinky, a little pale...so malabsorption does sound an option

Theoretically the heart rate should have decreased now the T4 is in range. Has the commented on this if present on last check?
Present Vet is somewhat cursory in his physical, checks

All this is quite interesting because recently I read somewhere ( think it was Idexx lab report ) where cobalamin ( Vitamin B12 ) and folate has been found to be lower in hyperthyroid cats-I believe even when it's controlled. I know that when B12 is supplemented it aids weight gain. I've noticed this with my IBD cat though diet in his case also helped in combating the malabsorbtion problems which were responsible for his weight loss. Also a specific blood test revealed he had these deficiencies ie cobalamin though folate was raised.

I wonder therefore if you might see a difference after some B12 injections. Do speak to the vet of course about this. At any rate being water soluble any excess is excreted so it won't do any harm. Think you can also buy it online without a prescription-I used methylcobalamin in my case.
I have methyl B12 tablets...I know less effective than injections but will start her on those...can I buy the injections online???

There is a chance also this may be a feature of the long term use of Felimazole-I've only used it preoperatively! Are you a member of the Yahoo group? They might have some more insight into this considering a lot of members there are very experienced in treating the conditon quite often in combination with others as well!
I do wish I had gone for the op when this was first diagnosed. I will look into the yahoo group

Thanks so much Ianthi....I have not booked an appointment yet, may consider taking her to a vet other than my regular one!
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Old 28-02-2011, 08:05 PM
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Re: Hyperthyroid

Yes, PP the pale stools ( usually soft as well ) could point to something like early stage malabsorption. In my case bloodwork revealed low protein ( albumin low which is a bit scary ) and calcium loss but his is more advanced though I must stress apart from odd vomiting spells he was virtually asymptomatic all his life ( until weight loss ) and he's 15 now! fPLI of >50 though very atypical in terms of appetite which is excellent!

What about worming? Rule these out just in case as well! Kidneys OK?

I would try giving the tablets first and see if they make a difference. Pedmeds do the injectable form though it's showing out of stock at present-not sure if methylcobalamin though! Otherwise vet might sell you some. You already have a diabetic cat so they know you're experienced in giving sub-c injections!

If she's fairly healthy otherwise perhaps the vet might still go ahead with the operation?

Will have a further think and let you know.....doing about 6 different things right now!

Last edited by Ianthi; 28-02-2011 at 11:21 PM..
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Old 01-03-2011, 04:35 AM
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Re: Hyperthyroid

Hi,..
If memory serves me well - which it often does not - I suggested that I strongly prefer radio-labeled iodine 123 or 131 which renders the individual hypothyroid which is easy to treat. Once you become what we call euthyroid then you will be able to lose weight - you will not gain weight.
useful one for the cat treatment,..
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Old 01-03-2011, 07:18 AM
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Re: Hyperthyroid

Quote:
Originally Posted by Davin View Post
Hi,..
If memory serves me well - which it often does not - I suggested that I strongly prefer radio-labeled iodine 123 or 131 which renders the individual hypothyroid which is easy to treat. Once you become what we call euthyroid then you will be able to lose weight - you will not gain weight.
useful one for the cat treatment,..
Davin....she is a very tiny 7.5lb cat so I don't want her to lose weight!
I wish the radio active iodine were more widely available....but also she is very dependeant on me and I do not think she would do well in solitary confinement , for weeks on end, also...she sleeps on the pillow next to me every night...and I think you are not allowed to pick them up for weeks after treatment.

Ianthi....thanks for the info for where to buy B-12, I am sure the injectable is cyanocobalamin form normally.
I just dont know if I have the nerve to put her through surgery at her age!
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Old 01-03-2011, 08:31 AM
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Re: Hyperthyroid

My old man is having his operation this morning. He is 17 at the mo. He couldn't tolerate the meds so only real option.

We decided not to do the radio active iodine treatment for the same reasons as you.

Good luck and hope all is well

Jen
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