toxicology testing on animals is extremely unreliable you might aswell toss a coin!

“Currently, nine out of ten experimental drugs fail in clinical studies because we cannot accurately predict how they will behave in people based on laboratory and animal studies.”
(Mike Leavitt, Health and Human Services Secretary, Food and Drug Administration Press Release Jan 12th 2006)

This means that even after all the animal tests, less than 1 in 10 drugs actually make it to become prescription drugs. This is a massive failure rate, which the FDA, one of the main drug regulators in the world, acknowledges.

Despite using over 100 million animals worldwide every year, less than 30 brand new drugs come onto the market on average every year in the US (the largest pharmaceutical market). This shows how hugely wasteful animal testing is.
(Anon 2008. Editorial: “Only 17 new molecular entities were approved by the US FDA in 2007, a fall from 53 in 1996”. Science 320, 1563)and Estimates of worldwide laboratory animal use in 2005. Alternatives to Laboratory Animals 36, 327–342.)

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"If the wolf is to survive, the wolf haters must be outnumbered. They must be outshouted, out financed, and out voted. Their narrow and biased attitude must be outweighed by an attitude based on an understanding of natural processes."
L David Mech

We have doomed the Wolf not for what it is, but for what we have deliberately and mistakenly perceived it to be..the mythologized epitome of a savage, ruthless killer..which is, in reality no more than a reflexed images of ourself." -Farley Mowat