i would agree with most above, re-book your hoilday if you can..
we dont go anywere when we have puppies we stay with bitches up until shes 2 weeks due and then until pups are around 5-6weeks..it reasures the bitch.some people might find this to much but we would never forgive our selves if something happened and we werent there to sort its..
your bitch could get worse by the time they are 3weeks old.
i personally wouldnt put them into bording in case of affecting its a very young age and if they do end up catching something there immune system might not cope with it or even worse if mum catches something and passes it on to pups..
good luck with pups and put some pictures up of them soon..!
kerry..x