Hi & welcome,
Six weeks is a bit too soon to be leaving littermates and mum in my opinion,the recommended age is 8 weeks.
Your puppy has been taken away from littermates and mum so will be missing them,your pup is in new surroundings with different noises,smells etc.

Feeding,your pup will need 4 small meals a day,a diet sheet and food should have been given by the breeder.Put the pups food down,leave it down for 20 mins if it has not been eaten pick it up and put it down for the next feed,keep repeating.Pups/Dogs will not starve themselves.

What are you feeding?
If it is canned/tinned food we usually find dogs will not drink alot of water as canned food contains a high percentage of water.

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