Originally Posted by Bobwilliams

Frontline is one of the most effective flea medication we've got and unfortunately one of the more expensive. The product has been around for a long time and we are starting to see some resistance, which is a concern and the reason we recommend using Frontline Plus rather than Frontline TopSpot. Frontline Plus contains (S)-methoprene, an ingredient that prevents reproduction by fleas that aren't killed by Frontline alone. Because Frontline depends on natural skin oils to spread itself around, it's best to wait about two days after bathing before applying the product and avoid bathing or swimming for a couple of days afterwards.

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Bobwilliams
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