i'm sure that this is something many of you won't agree with but i purchased a book called how to train your beagle and it states in it that if they are biting very hard on your hand and nothing else works then gently squeeze their top lip together with your thumb and forefinger using the hand they are biting until they let go. they soon learn that by biting they will get discomfort and it stops them from doing it. you do not pinch hard or hurt them you just apply a little bit of pressure.