Hiya, i dont worm mine untill they are 6 weeks using panacur paste, then every 2 weeks untill they are 12 weeks old. After that i worm them monthly untill 6 months. Unless they have any signs of worms i would wait .It can knock them about abit ,i think 2 weeks is too young unless absolutley necessary.
Was mom up to date with her worming before she was pregnant?
I use frontline to flea them, its safe to use at 8 weeks as long as your kittens weigh over 1kg.