The only thing with useing his crate to isolate is that it then or may becomes an unfriendly place to be, so when you need him to be calm and happy in there say when you are out he may not want to be in thier. Ours all love the crate and go in to chill out, I used the baby gate method in several rooms of the house to have time out for the pups, they could then still have a roam around and still see us, they dont feel hemmed in.

Jasper was the worst puppy Iv ever had with biteing as a pup my hands were a mess but with removeing myself or removeing him to an area of the house gated off plus the yelping when he bit/nipped and working through this over several weeks he stopped and became a little pup who was a delight. I also had to increase the stimulus he was getting in the form of brain activities, not excercise he was getting loads of this, so we played hide and seek with treats, I got some intelli toys and a kong stuffed with part of his dinner to keep him focused, you can Iv heard even freeze wet food in the kong to make it harder, but iV never done this so dont know if this is an ok thing to do Just hear it said.
We couldnt even stroke his head put his collar on he just wanted to nip all the time and it does feel like a bite cause it hurts and draws blood. 7 Years on Jasper is one of the sweetest dogs you could ever meet and everyone that meets him wants to take him home and he loves to be stroked and cuddled

But must say Jasper was a porrly pup and had some health issues RE digestion/ higher levels of something to leave him pre disposed to pancreatitis so he wasnt getting thwe right nutrients absorbed. It may well be worth getting him checked over fully by the vet but Im sure its just a bolshy strong willed little pup you have there

Sorry for the essay but just a few things we did that worked

Good luck again