Personally speaking, I got up in the night when I decided too and not when he cried, purely because the first few days he was home he cried constantly while he was alone and awake. Tried getting up when he cried but it wasn't to go toilet it was for people, as he didn't need to go.
He hasn't ever made a noise to say he needs the toilet either, Rupert would just go, lol!
Up to you, as long as its a toilet break for pup and he/she knows its not playtime you should be fine

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While some may see them as the crazy ones, we see genius. Because the people who are crazy enough to think they can change the world, are the ones who do...